Chemical Name: N-acetyl-para-aminophenol
Trade Name: ACETAMINOPHEN
Introduction:
Acetaminophen is a pain reliever and a fever reducer. Common conditions that acetaminophen treats include headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. Acetaminophen was first made in 1877. It is the most commonly used medication for pain and fever in both the United States and Europe.
General Applications:
Acetaminophen is used in various forms such as tablet, drops, suppository, oral syrup, It is also employed in drug formulations with other APIs like antihistamines in order to reduce fever, relive pains and decrease cold symptoms.
| TEST | STANDARD | Unit | Ref |
| IR spectra | Spectrum obtained with standard Acetaminophen | – | USP41-NF36 |
| Organic Impurities | Acetaminophen Related Compound B
NMT 0.05% |
%wt | USP41-NF36 |
| Acetaminophen Related Compound C
NMT 0.05% |
|||
| Acetaminophen Related Compound D
NMT 0.05% |
|||
| Acetaminophen Related Compound I
NMT 0.001% |
|||
| Individual unspecified Impurity
NMT 0.05% |
|||
| Total Impurities
NMT 0.1% |
|||
| Loss on drying | Max 0.5 | %wt | USP41-NF36 |
| Residue on Ignition | Max 0.1 | %wt | USP41-NF36 |
| Assay(on the dried basis) | 98 – 102 | %wt | USP41-NF36 |
| LIMIT OF FREE 4-AMINOPHENOL | NMT 0.005 | %wt | USP41-NF36 |
| Heavy metals | Max 10 | ppm | USP41-NF36 |
| Residual solvents | Defined as Organic volatile chemicals | ppm | USP41-NF36 |
| Packing: | PE bags in Paper Drums |
| Net Weight: | 25 Kg’s |
| Gross Weight: | 40 Kg’s |
| No. Of Bags on Pallet: | 6 |
| No. Of Pallet in 20″ FCL: | 20 |
| Shelf Life: | 2 Years |
| IMCO Class: | Non-Imco |
Safety, Handling & Storage:
Full information on the safety, handling and storage of KECASs is available in the corresponding Material Safety Data Sheet (MSDS).
